The starting material for making the product is bovine blood, collected from cows. It undergoes a process of multiple separation techniques, including filtration, diafiltration, centrifugation, chromatography, and ultrafiltration, followed by polymerization and fractionation for sizing, including unique co-polymer reaction steps, ending with a sterile fill and finish step. To monitor the reproducibility and stability of the process, several analytical methods are used to measure the impurities profile, endotoxins, and bio burden, as well as a product quality assay.